5-Amino-1MQ

5-Amino-1MQ in Laboratory Research

5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small molecule rather than a peptide. It acts as an inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide and thereby diverts it away from NAD+ salvage.

That relationship makes it a common companion compound in metabolic research, where it is used to manipulate NNMT activity in cell-based systems.

Research Applications & Study Focus

Researchers use 5-Amino-1MQ to probe NNMT activity, nicotinamide flux, and adipocyte metabolic signalling, frequently pairing it with NAD+ work to trace how salvage-pathway inhibition shifts the NAD+ pool.

Its consistent specification lets laboratories reproduce enzyme-inhibition conditions precisely across experiments.

Purity, Handling & Verification

Each batch is supplied as a sealed, lyophilized vial and is independently analysed by a third-party laboratory using HPLC and mass spectrometry; the full certificate of analysis is published against its lot number, so results can be verified before use. Store the lyophilized material cool, dry and out of direct light, and reconstitute with bacteriostatic water under standard aseptic laboratory practice.

This material is offered strictly for in vitro laboratory research use only. It is not for human or veterinary consumption, and not for diagnostic or therapeutic use.